BigQuery is Google’s fully managed, petabyte scale, low cost analytics data warehouse. BigQuery is NoOps—there is no infrastructure to manage and you don’t need a database administrator—so you can focus on analyzing data to find meaningful insights, use familiar SQL, and take advantage of our pay-as-you-go model.

That’s great, right?

So let’s get started. At the end of this, you will be able to you will use Google Cloud Client Libraries for .NET to query BigQuery public datasets with C#.

This quick course will go over:

• Setup and Requirements
• Enabling the BigQuery API
• Authenticating API requests
• Setup Access Control
• Installing the BigQuery client library for C#
• Query the works of Shakespeare
• Query the GitHub dataset
• Caching and statistics
• Loading data into BigQuery

Get Started Now

As lead for analytics and AI solutions at Google Cloud, my team works with startups building on Google Cloud. This puts us in the fortunate position to learn from founders and engineers about how early-stage startups’ investments can either constrain them or position them for success, even at the seed level. In this post, I want to share a few of the best practices to keep in mind as you’re building. 

Understand your value proposition before diving into a technology stack

If you’re launching a startup in the cloud, you’re no doubt thinking about a technology stack, but it’s important to step back a bit and think carefully about the major value proposition that your startup offers to your customers. That value proposition is going to fundamentally drive the kind of technology that you should pick.

For example, does your system need processing in real time, or can it be done in a batch mode? Can you rely on once-a-day insights or do the insights have to come in as events happen?

Additionally, what kind of latency will your customers face? That latency makes your value proposition either usable or unusable. Early on in Google’s development, leaders realized that no one was going to wait more than a few hundred milliseconds for a web page to show them their results, and that realization drove the technology decisions that have allowed Google to scale from being a startup in a garage to being a trillion dollar company. Your startup needs to define its value to customers with this level of specificity before it can build a technology stack suited to its needs. 

Focus on customer interactions

A few companies have gracefully pulled off big IT pivots that reshaped their value proposition. Netflix, for example, moved from mostly sending DVDs through the mail to becoming a streaming service and major content producer. That’s a huge shift in the user experience and the technology stack necessary to support it, even if the underlying value proposition (i.e., get content to customers) was broadly the same. But it’s also an outlier. If you’re planning for potential changes of this magnitude, rather than focused on getting your value proposition to users, you probably need to sharpen what that value proposition is.

Specifically, you need a clear vision of how customers will access and interact with your business. Typically, they’ll do so over a website or a mobile app, but there are still so many variables. 

Are customers going to transmit documents? If so, in what format? Is handwriting supported or is input limited to typing? Can they use images for optical character recognition? Will it mostly be forms? Will the data be structured or unstructured? If all that sounds  a little overwhelming, don’t worry, it’ll seem simpler by the end of this article—but also be aware: we’re just getting warmed up.

Imagine that most of your customers will access your business via voice, so you know you’ll want to prioritize conversational workflows. That’s a start—but dig deeper.  Even if we suppose you’re usingDialogflow, a Google Cloud conversational AI platform that lets you build and deploy virtual agents, we’re still not really seeing the value proposition.  How will all this work, from the beginning of a typical full customer interaction to the resolution? How many interactions will have to be facilitated over low-bandwidth connections, for example? When it comes to user interactions, make sure you can see an end-to-end use case.

Another example: you’re building a retail website, and one of your end-to-end use cases involves the customer asking if a certain amount of a given product is in stock, whether it’s one unit of the product, ten or hundreds. If the product is not sufficiently stocked, you want your app to offer similar items that are. Will your technology stack support this end-to-end use case?

These considerations are not an argument for premature optimization. There’s value in moving fast, getting minimum viable products to users, and then iterating. But in the early stages, you only get one chance to start on the right foot—and how you navigate that chance will influence a lot of dollars and effort down the road. You need to make sure you have business use cases, not just an idea, before you can start designing a technology stack.  

Here’s how to get in the right frame of mind. Pick three use cases: two that are “bread and butter” and one that is technologically complex.  Make sure your proposed technology stack can support all three, end to end. 

Default toward higher levels of abstraction

Now that we’re in the right frame of mind, we’re ready to think about the technology stack more directly. 

As a startup, you’ll need to conserve resources, and to do that, you’ll want to build at the highest level of abstraction possible for your value proposition. For example, you probably don’t want your people setting up clusters. You don’t want them configuring things if they can use a fully managed service. You want them focused on building your prototype, not managing infrastructure.

This focus has definitely informed how we create products at Google Cloud, as our canonical data stack—Pub/Sub, Dataflow, BigQuery, and Vertex AI—consists of auto-scaling and serverless products.

But management of infrastructure is not the only place where you should err toward a less-is-more philosophy. 

When it comes to architecture, choose no-code over low-code and low-code over writing custom code. For example, rather than writing ETL pipelines to transform the data you need before you land it into BigQuery, you could use pre-built connectors to directly land the raw data into BigQuery. That’s no code right there. Then, transform the data into the form you need using SQL views directly in the data warehouse. This is called ELT, and it is low code. You will be a lot more agile if you choose an ELT approach over an ETL approach. 

Another place is when you choose your ML modeling framework. Don’t start with custom TensorFlow models. Start with AutoML. That’s no-code. You can invoke AutoML directly from BigQuery, avoiding the need to build complex data and ML pipelines. If necessary, move on to pre-built models from TensorFlow Hub, HuggingFace, etc. That’s low-code. Build your own custom ML models only as a last resort.

Focus on getting your vision to market, not chasing technology hype  

The goal is to pick the right technology stack for bringing your vision to market, generating value for customers, conserving resources, and maintaining flexibility for growth. Early IT investments should usually gravitate toward things that preserve flexibility, such as managed services built on standard protocols or open APIs, but they needn’t always rush to the flashiest technologies.  The answer isn’t always ML, for example. The answer might be heuristics to start, with a path to ML once you have collected enough data. You want to make sure that your intelligence layer has enough abstraction so you can mark it up with simple rules at first, but then replace it with a more robust system as you go along. 

Launch and iterate fast with these principles 

The preceding discussion is a reminder that your most expensive resource is your people—and that you really want them to be focused on building your prototype, minimum viable product or production app  You want to launch fast and iterate fast, and the only way you can do that is by focusing on the things that differentiate you. 

But regardless of the technologies you use, the bottom line is the same: follow these four principles. 

• Figure out your major value proposition and design your tech stack around it. 
• Be very careful about user interactions. User experience is super important; you need to make sure you deliver the kind of experience that your customers have grown to expect.
• When you’re building, pick the highest possible level of abstraction possible—the most fully managed tools and no-code/low-code frameworks that give you the functionality that you need. 
• Instead of choosing new or flashy technologies, consider if you can build a “good enough” minimum viable product quickly and come back to a better implementation later. 

To learn more about why startups are choosing Google Cloud, click here.

The COVID-19 pandemic continues to push the healthcare and life sciences industry in entirely new ways. In record time, we’ve witnessed public health officials, vaccine developers, equipment manufacturers, and essential workers take life saving actions—regularly putting their own lives at risk—to respond to the exceptional challenges of our time. 

Yet after all the turmoil and uncertainty of the pandemic, record breaking levels of investment continue to come into the market to fuel innovations. 

Vaccine development is now measured in weeks rather than years; providers are leveraging telehealth technologies to improve the physician and patient experience; and individuals have embraced a variety of devices to assume greater ownership and control of their personal health. 

With that in mind, here are five of the many innovations I see driving healthcare and life sciences for at least the next 12 months: 

1. Unleashing the power of healthcare and life sciences data

People have arguably never had as much access and understanding to their personal health data than they can in 2022. They have the ability to understand their genetic makeup, medical history, family history, and activity levels to ensure they are living a healthy lifestyle. Taken together, this longitudinal profile can become the basis for more personalized medicine. Add wearable devices to the mix and patients gain real- or near-real-time updates on their health status. 

Further, global regulatory agencies have continued to mandate the need for providers to maintain a longitudinal health record that provides a holistic view of the patient across all the encounters they have had with a health system. Physician surveys conducted by the The Harris Poll and Google Cloud show that a 360-degree view of the patient, across all provider encounters, leads to faster, more accurate diagnosis, and better outcomes. 

If secure data access and interoperability can begin to include insurers, researchers, public health officials, and others in the field, the powerful network effects benefiting patients will only grow. When combined with those longitudinal phenome profiles, the opportunities for personalized and preventative medicine enter a whole new era.

2. Healthcare and life sciences M&A boom continues

Although the pandemic initially slowed activity on mergers and acquisitions in the early part of 2020, the healthcare and life sciences industry has seen a rapid rebound and acceleration of deals ever since. The success of COVID-19 vaccines, the importance of telehealth, and the focus on molecular modeling and genomic-based drug development have all boosted investment as organizations look to enter new markets, develop new therapies, and leverage low interest rates while they last. 

In 2021, the total funding of US digital health startups surpassed $29 billion across 729 deals, according to advisory Rock Health. That’s almost double the levels of 2020, which itself set records. Analysts at PWC meanwhile estimate M&A investments in biopharmaceutical and life sciences could approach $400 billion this year across all sub-sectors

Clearly, the pandemic has been a primary driver of investment as the focus on healthcare has dramatically increased. Yet the increased activity also reflects changing business models and emerging technologies that are now required to compete in the rapidly evolving space. For organizations to capitalize on these investments, it will take not only great vision and intellectual property but also the right technologies—like cloud—and the right data interoperability models, to make partnerships and acquisitions more scalable, feasible, and seamless.

3. Transforming the patient experience at a new rate

The pandemic has shined a spotlight on the inefficiencies and complexities that exist in healthcare markets across the globe. As wave after wave has surged, global healthcare systems remain overwhelmed on most every aspect of patients’ treatment journeys. Even before COVID-19, healthcare was already one of the largest spend areas for governments around the world. The pandemic has only exacerbated the known issues. 

Clearly, administrators, regulators, physicians, nurses, and patients would agree that the processes and models need to change. There’s a need to maintain this momentum and even increase the tempo to achieve lasting change.

Take telehealth. Within months of the start of the pandemic, providers moved to provide more remote capabilities so physicians could still meet with patients virtually to ensure health and safety on all sides. Payers recognized the importance of telehealth and began to update reimbursement rules. And organizations are now reimagining policies in areas such as prior authorization, submission, and adjudication to reduce complexity and bureaucracy while improving responsiveness.

Looking beyond the system, organizations are also recognizing and deepening their understanding of the structural and social determinants of health that impact patient care and health outcomes, especially for historically underserved communities.  Private and public sectors are learning from, and increasingly partnering with, the social sciences, public health, biomedical informatics, computer science, public policy and community groups around how to build a mI’ore equitable and inclusive consumer products and Health IT strategies. 

The newfound levels of transparency, visibility, and accountability that patients, caregivers, and organizations are achieving will ultimately increase competition and provide a more effective, equitable, efficient and, above all, healthier marketplace for all patients. As we move past the worst of the pandemic, regulators and organizations should keep fighting for progress over business as usual.

4. AI is now a core competency for Drug Development

The ability of organizations like Pfizer, Moderna, Johnson & Johnson, and Astrazeneca to develop COVID-19 vaccines has been a remarkable accomplishment—particularly the historic speed with which they were created and deployed. This innovation acceleration was largely enabled by the use of new drug development platforms that allow researchers to use artificial intelligence and machine learning to model protein and cellular interactions to rapidly advance the science.

No longer must researchers rely on traditional laboratory testing (and retesting). With their improved understanding of the molecular and genetic structure of a patient and, for example, their tumor, researchers can use AI to enable simulations on computers rather than testing in live conditions. This technology can process thousands, even millions of simulations to help  identify high-potential candidates for treatment consideration and subsequent analysis. 

AI-enabled drug discovery models can eliminate months and years from the research process, which can reduce the time to develop a drug and accelerate the time to treatment for an individual patient. As just one example, consider the work on AlphaFold2 by Google’s DeepMind unit who leverages AI to predict effective protein shapes for new drugs. Healthcare and life sciences organizations already recognize the potential of AI. Now comes the investments to leverage this rapidly evolving technology to support their efforts now and in the future.   

5. Ecosystem partnerships tackle complexity and spur innovation

As the importance and growth of the healthcare and life sciences industry continues, we will see even more new players and partnerships emerging to address old problems in new ways. This trend will touch all aspects of the healthcare value chain and will, increasingly, see three- and four-player partnerships emerge to address the complex challenges of today’s healthcare marketplace.

Technology will continue to play a key role as capabilities and platforms will transform all aspects of the marketplace. Cell phones, wearable devices, and other technologies will provide real-time updates and notifications to patients on everything from glucose levels to payments for healthcare services. Voice recognition software will document physician and patient discussions to reduce the burden of record keeping. Real-world data will be used to simplify and confidentially recruit patients for participation in clinical trials. 

New players will continue to enter the market to improve health outcomes and reduce costs. Major retailers are among the companies extending their pharmacies to provide additional diagnostic and concierge services, saving patients from additional appointments while boosting prevention. Community organizations are emerging to help identify and care for underserved communities whose health outcomes are significantly lower than the average patient. 

For all the exhausting and heart-wrenching challenges of the past two years, the opportunities the pandemic has laid bare cannot be overlooked. We owe it to those who have worked and fought so hard for every life to forge even more new partnerships—and make it easier to do so—so that the next crisis, when it does arise, will never be as bad as the one we’re now conquering. Technology can be the enabler in this effort and help bring us together to continue to conquer the challenges that lie ahead.

Vertex AI launched with the premise “one AI platform, every ML tool you need.” Let’s talk about how Vertex AI streamlines modeling universally for a broad range of use cases. 

The overall purpose of Vertex AI is to simplify modeling so that enterprises can fast track their innovation, accelerate time to market, and ultimately increase return on ML investments. Vertex AI facilitates this in several ways. Features like Vertex AI Workbench, for example, speed up training and deployment of models by five times compared to traditional notebooks. Vertex AI Workbench’s native integration with BigQuery and Spark means that users without data science expertise can more easily perform machine learning work. Tools integrated into the unified Vertex AI platform, such as state of the art pre-trained APIs and AutoML, make it easier for data scientists to build models in less time. And for modeling work that lends itself best to custom modeling, Vertex AI’s custom model tooling supports advanced ML coding, with nearly 80% fewer lines of code required (compared to competitive platforms) to train a model with custom libraries. Vertex AI delivers all this while maintaining a strong focus on Explainable AI. 

Yet organizations with the largest investments in AI and machine learning, with teams of ML experts, require extremely advanced toolsets to deliver on their most complex problems. Simplified ML modeling isn’t relegated to simple use cases only.

Let’s look at Vertex AI Neural Architecture Search (NAS), for instance. 

Vertex AI NAS enables ML experts at the highest level to perform their most complex tasks with higher accuracy, lower latency, and low power requirements. Vertex AI NAS originates from the deep experience Alphabet has with building advanced AI at scale. In 2017, the Google Brain team recognized we need a better way to scale AI modeling, so they developed Neural Architecture Search technology to create an AI that generates other neural networks, trained to optimize their performance in a specific task the user provides. To the astonishment of many in the field, these AI-optimized models were able to beat a number of state of the art benchmarks, such as ImageNet and SOTA mobilenets, setting a new standard for many of the applications we see in use today, including many Google-internal products. Google Cloud saw the potential of such a technology and shipped in less than a year a productized version of the technique (under the brand AutoML). Vertex AI NAS is the newest and most powerful version of this idea, using the most sophisticated innovation that has emerged since the initial research.

Customer organizations are already implementing Vertex AI NAS for their most advanced workloads. Autonomous vehicle company Nuro is using Vertex AI NAS, and Jack Guo, Head of Autonomy Platform at the company, states, “Nuro’s perception team has accelerated their AI model development with Vertex AI NAS. Vertex AI NAS have enabled us to innovate AI models to achieve good accuracy and optimize memory and latency for the target hardware. Overall, this has increased our team’s productivity for developing and deploying perception AI models.” 

And our partner ecosystem is growing for Vertex AI NAS. Google Cloud and Qualcomm Technologies have collaborated to bring Vertex AI NAS to the Qualcomm Technologies Neural Processing SDK, optimized for Snapdragon 8. This will bring AI to different device types and use cases, such as those involving IoT, mixed reality, automobiles, and mobile.

Google Cloud’s commitments to making machine learning more accessible and useful for data users, from the novice to the expert, and to increasing the efficacy of machine learning for enterprises are at the core of everything we do. With the suite of unified machine learning tools within Vertex AI, organizations can take advantage of every ML tool they need on one AI platform. 

Ready to start ML modeling with Vertex AI? Start building for free. Want to know how Vertex AI Platform can help your enterprise increase return on ML investments? Contact us.