Dr. Elliot Smith cannot be accused of lacking ambition. A high achiever with a Ph.D. in Electrical Engineering and a specialist in magnetic resonance imaging (MRI) systems, Smith aims to deliver top quality healthcare to anyone in the world — regardless of their location or wealth.

Dr. Smith has already made strides on this journey with his Brisbane, Queensland-headquartered business, Maxwell MRI. “I saw there was a big gap in the market around automating the diagnosis of health conditions,” he says. “Existing processes were typically manual and involved a lot of people.”

Artificial intelligence (AI) and machine learning can remove a key obstacle to scaling out medicine and improve the efficiency and accuracy of diagnosing conditions, the healthcare entrepreneur believes.

“Our grand vision is to build an AI doctor that anyone can receive affordable support from and connect to in order to obtain results,” explains Dr. Smith.

Maxwell MRI presently enables clinicians to submit anonymised MRI scans to a machine learning enabled AI platform to help diagnose prostate cancer. The service is sold to clinicians who can then charge a per-session fee to clients. As well as obtaining results for individual cases, the MRI scans and associated information is used to ‘train’ the platform to deliver accurate diagnoses faster and in a more affordable way than existing systems do.

Dr. Smith and his team started by running a number of functions and processes on a single server with graphics processing units (GPUs) and sizable hard disk capacity. However, this infrastructure could not scale to support the planned growth of the business. Each case Maxwell MRI processes involves about 200MB of data in MRI scans alone. Once supplementary data, blood test result, pathology results and genetic information is included, this load can reach more than 1GB of data per patient.

The business aimed to process 150,000 cases by the end of 2018. This required a service that could deliver massive scale in data storage and compute, and could easily be accessed from any location. “We wanted to move from three GPUs to 30 GPUs without having to buy more servers or other associated equipment, so the cloud was the natural next step,” says Dr. Smith.

Maxwell MRI evaluated Google Cloud Platform (GCP) and determined that the managed services component of GCP would remove the burden of infrastructure deployment and administration. In addition, Google Cloud Machine Learning Engine would enable the business to scale to as many GPUs as needed to meet demand.

Maxwell MRI started with some small experiments to determine that GCP met all its requirements and completed its migration to the platform in February 2017. “We really started to scale up the data we had and consequently our computing requirements at that time,” Dr. Smith says.

The Maxwell MRI platform features an upload service that enables clinicians to upload imaging and associated data. This service triggers several different upload pipelines that clean and standardise data. They then write imaging data to Google Cloud Storage, and more structured data to a combination of Google Cloud Datastore and Google Cloud Spanner.

The platform then converts the information into records that can be used to ‘train’ new machine learning configurations or run evaluations through existing machine learning pipelines.

“The tasks we perform including segmenting various anatomical regions for analysis and sending those results back into Google Cloud Storage,” says Dr. Smith. “This then commences that repeated process of running Google Cloud Dataflow pipelines and machine learning algorithms, and presenting those outcomes back to the clinicians.”

Existing Literature Validated

The data processed and analysed to date has, Dr Smith says, enabled Maxwell MRI to help validate existing literature that indicates clinicians lack confidence in existing early-stage testing procedures for prostate cancer. This prompts them to move quickly to the biopsy stage to assure themselves their diagnosis is valid. “New technologies have a lot of potential to rectify this situation and guide treatment to be more accurate, specific and cost-effective,” he says.

Results Delivered in 10-15 Minutes

More specifically, using GCP has enabled Maxwell MRI to guarantee to clinicians that results will be delivered within minutes. “Clinicians are used to getting results back in two days to a week,” says Dr. Smith. “We’re saying that with our platform running on GCP we’ll deliver you results in 10 to 15 minutes, regardless of the number of patients coming in.”

Running on GCP has enabled the business to accelerate its development cycles, test new ideas easily on a subset of data, test in parallel and deliver new services considerably faster than in another environment. In addition, the flexible GCP charging model aligned with the ability to scale compute capabilities quickly and easily has enabled the fledgling business to control its costs.

Google technologies are poised to play an integral role in the business’s future. “With Google available, it doesn’t make sense for us to use our own infrastructure,” Dr. Smith says. “Our expertise in AI, machine learning and clinical engagement complements cloud platform specialties of infrastructure, managed services and ease of use. We see a bright future ahead in helping to transform healthcare globally.”

This week, the Vera C. Rubin Observatory is launching the first preview of its new Rubin Science Platform (RSP) for an initial cohort of astronomers. The observatory, which is located in Chile but managed by the U.S. National Science Foundation’s NOIRLab in Tucson, AZ and SLAC in California, is jointly funded by the NSF and the U.S. Department of Energy. The platform provides an easy-to-use interface to store and analyze the massive datasets of the Legacy Survey of Space and Time (LSST), which will survey a third of the sky each night for ten years, detecting billions of stars and galaxies, and millions of supernovae, variable stars, and small bodies in our Solar System.

The LSST datasets are unprecedented in size and complexity, and will be far too large for scientists to download to their personal computers for analysis. Instead, scientists will use the RSP to process, query, visualize, and analyze the LSST data archives through a mixture of web portal, notebook, and other virtual data analysis services. An initial launch with simulated data, called Data Preview 0, builds on the Rubin Observatory’s three-year partnership with Google to develop an Interim Data Facility (IDF) on Google Cloud to prototype hosting of the massive LSST dataset. This agreement marks the first time a cloud-based data facility has been used for an astronomy application of this magnitude.

Bringing the stars to the cloud

For Data Preview 0, the IDF leverages Cloud Storage, Google Kubernetes Engine (GKE), and Compute Engine to provide the Rubin Observatory user community access to simulated LSST data in an early version of the RSP. The simulated data were developed over several years by the LSST Dark Energy Science Collaboration to imitate five years of an LSST-like survey over 300 square degrees of the sky (about 1,500 times the area of the moon). The resulting images are very realistic: they have the same instrumental characteristics, such as pixel size and sensitivity to photons, that are expected from the Rubin Observatory’s LSST Camera, and they were processed with an early version of the LSST Science Pipelines that will eventually be used to process LSST data. “This will be the first time that these workloads have ever been hosted in a cloud environment. Researchers will have an opportunity to explore an early version of this platform,” says Ranpal Gill, senior manager and head of communications at the Rubin Observatory.

Broadening access for more researchers

Over 200 scientists and students with Rubin Observatory data rights were selected to participate in Data Preview 0 from a pool of applicants that represents a wide range of demographic criteria, regions, and experience level. Participants will be supported with resources such as tutorials, seminars, communication channels, and networking opportunities—and they will be free to pursue their own science at their own pace using the data in the RSP. 

“The revolutionary nature of the future LSST dataset requires a commensurately innovative system for data access and analysis paired with robust support for scientists,” says Melissa Graham, lead community scientist for the Rubin Observatory and research scientist in the astronomy department at the University of Washington. “I’m personally excited to enhance my own skills by using the RSP’s tools for big data analysis, while also helping others to learn and to pursue their LSST-related science goals during Data Preview 0.” 

At the same time, the fact that the RSP is hosted in the cloud provides researchers at smaller institutions access to state-of-the-art astronomy infrastructure that is comparable to that of the largest national research centers.

The launch benefits the observatory too: the development team can learn what researchers are interested in while also testing and debugging the platform. Graham says that “the platform is still in active development so researchers using it will be able to follow along in the progress, and provide feedback on ways that we can optimize the development of the tools.”

Next steps

The LSST aims to begin the ten-year survey in 2023-24 and expects it to include 500 petabytes of data. Through the cloud, Google aims to help make this extraordinary project scalable and accessible to researchers everywhere. To learn more about Data Preview 0, watch this video.

Want to ramp up your own research in the cloud? We offer research credits to academics using Google Cloud for qualifying projects in eligible countries. You can find our application form on Google Cloud’s website or contact our sales team.